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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEATR1
All Species:
19.09
Human Site:
Y771
Identified Species:
32.31
UniProt:
Q9H583
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H583
NP_060542.4
2144
242370
Y771
P
V
E
L
W
A
H
Y
V
E
E
L
N
S
T
Chimpanzee
Pan troglodytes
XP_001156974
2144
242420
Y771
P
V
E
L
W
A
H
Y
V
E
E
L
N
S
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536334
2141
242568
Y771
P
V
Q
L
W
A
H
Y
I
E
Q
L
N
A
A
Cat
Felis silvestris
Mouse
Mus musculus
NP_659084
2143
242053
Y771
P
E
E
L
W
V
R
Y
V
Q
E
L
H
G
A
Rat
Rattus norvegicus
NP_001101888
2143
241191
Y771
P
E
E
L
W
V
H
Y
V
Q
Q
L
H
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422958
2155
244590
Y773
P
V
G
L
L
T
A
Y
I
E
K
L
N
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SY48
2159
242032
F763
V
C
V
A
L
G
E
F
L
Q
K
I
S
C
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VM75
2096
237201
T762
L
Y
V
D
F
L
L
T
L
V
K
N
T
K
W
Honey Bee
Apis mellifera
XP_393800
2028
231830
V731
P
L
Q
V
G
T
Y
V
L
E
M
V
H
R
R
Nematode Worm
Caenorhab. elegans
Q23495
1650
185210
K412
G
N
I
F
D
N
K
K
K
L
K
S
N
I
R
Sea Urchin
Strong. purpuratus
XP_794611
1635
181917
H397
R
E
I
H
V
E
S
H
I
V
V
D
T
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Z4
2001
224001
H729
L
V
E
A
F
M
M
H
P
A
D
Y
I
Q
W
Baker's Yeast
Sacchar. cerevisiae
P42945
1769
200063
I531
T
F
L
L
R
V
T
I
S
P
A
A
P
T
A
Red Bread Mold
Neurospora crassa
Q7RZM8
1788
196873
A550
A
P
T
K
L
F
Y
A
S
F
Y
M
R
L
W
Conservation
Percent
Protein Identity:
100
99.5
N.A.
89.7
N.A.
83.8
84.9
N.A.
N.A.
65.5
N.A.
54.5
N.A.
28.6
30.5
21.1
24.4
Protein Similarity:
100
99.8
N.A.
95
N.A.
92.1
92.7
N.A.
N.A.
80.5
N.A.
73
N.A.
49.4
50.8
38.9
43.2
P-Site Identity:
100
100
N.A.
66.6
N.A.
53.3
53.3
N.A.
N.A.
53.3
N.A.
0
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
66.6
73.3
N.A.
N.A.
66.6
N.A.
40
N.A.
20
60
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.4
21.2
23
Protein Similarity:
N.A.
N.A.
N.A.
43.4
40.2
42.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
0
22
8
8
0
8
8
8
0
15
29
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
8
0
0
0
0
0
8
8
0
0
8
% D
% Glu:
0
22
36
0
0
8
8
0
0
36
22
0
0
0
0
% E
% Phe:
0
8
0
8
15
8
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
8
0
8
8
0
0
0
0
0
0
0
15
8
% G
% His:
0
0
0
8
0
0
29
15
0
0
0
0
22
0
0
% H
% Ile:
0
0
15
0
0
0
0
8
22
0
0
8
8
8
0
% I
% Lys:
0
0
0
8
0
0
8
8
8
0
29
0
0
8
0
% K
% Leu:
15
8
8
50
22
8
8
0
22
8
0
43
0
8
0
% L
% Met:
0
0
0
0
0
8
8
0
0
0
8
8
0
0
0
% M
% Asn:
0
8
0
0
0
8
0
0
0
0
0
8
36
0
0
% N
% Pro:
50
8
0
0
0
0
0
0
8
8
0
0
8
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
22
15
0
0
8
0
% Q
% Arg:
8
0
0
0
8
0
8
0
0
0
0
0
8
8
22
% R
% Ser:
0
0
0
0
0
0
8
0
15
0
0
8
8
22
0
% S
% Thr:
8
0
8
0
0
15
8
8
0
0
0
0
15
8
15
% T
% Val:
8
36
15
8
8
22
0
8
29
15
8
8
0
0
0
% V
% Trp:
0
0
0
0
36
0
0
0
0
0
0
0
0
0
22
% W
% Tyr:
0
8
0
0
0
0
15
43
0
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _